About PLN Genetic Heart Disease
For our heart to beat, calcium ions in the heart muscle cells are important. The phospholamban (PLN) protein plays an important role in the calcium balance of the heart muscle cells.
Heart disease is caused by a loss of cardiomyocytes (heart muscle cells), usually because of a heart attack or weakening of the cardiac muscle cells. Heart contractions and the ability to pump blood through our bodies depend on well orchestrated calcium movements in and out of the cell. The PLN (phospholamban) gene is a key regulator of the pump that controls calcium cycling. Scientific names for this PLN gene mutation are c.40_42del AGA and PLN.Arg14del. More about PLN Support Us
Latest news & blog articles
Documentary “Aan het hart” (to the heart)- by Mirjam Bartelsman
Mirjam Bartelsman made the dramatic Dutch documentary “Aan het hart”. What would you do if you found out that there…
PhD!
Patricia Vanhooydonck-vd Hoogen will obtain her PhD at Utrecht University on September 14. For the past 4 years, as a…
Latest PLN Research results, developments & events
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PhD!
Patricia Vanhooydonck-vd Hoogen will obtain her PhD at Utrecht University on September 14. For the past 4 years, as a…
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Cycling for PLN
An alternative Monstertocht: the “Elfstedentocht”! On September 12, 33 (!) cardiologists, doctors and general practitioners and others involved will cycle…
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PLN carrier in the Corona crisis | Casper’s story
PLN carrier during the Corona crisis… how is that? What do encounter? And how do you deal with this? Casper…
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