About PLN Genetic Heart Disease
For our heart to beat, calcium ions in the heart muscle cells are important. The phospholamban (PLN) protein plays an important role in the calcium balance of the heart muscle cells.
Heart disease is caused by a loss of cardiomyocytes (heart muscle cells), usually because of a heart attack or weakening of the cardiac muscle cells. Heart contractions and the ability to pump blood through our bodies depend on well orchestrated calcium movements in and out of the cell. The PLN (phospholamban) gene is a key regulator of the pump that controls calcium cycling. Scientific names for this PLN gene mutation are c.40_42del AGA and PLN.Arg14del. More about PLN Support Us
Latest news & blog articles
PLN Elfstedentocht
Here we go again! YES!! On Saturday September 11, 2021 we will cycle the PLN Elfstedentocht again! Our cardiologists, doctors…
Summary of Daans Cycletour
Daan Obdeijn cycled his own alternative Elfstedentocht around Deventer and raised a great amount for PLN with his friends! What…
Latest PLN Research results, developments & events
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New article in AHA Journals
An article about a study for PLN has been published in a highly regarded Journal. The study explores potential therapeutic…
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Funding for “Harvey”
NWO OTP has awarded funding to a research team supported by the PLN Foundation, led by Professor Doevendans. With the…
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You Tube
Did you know that we have a You Tube page with English videos of researchers? In these videos they explain…
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