About PLN Genetic Heart Disease
For our heart to beat, calcium ions in the heart muscle cells are important. The phospholamban (PLN) protein plays an important role in the calcium balance of the heart muscle cells.
Heart disease is caused by a loss of cardiomyocytes (heart muscle cells), usually because of a heart attack or weakening of the cardiac muscle cells. Heart contractions and the ability to pump blood through our bodies depend on well orchestrated calcium movements in and out of the cell. The PLN (phospholamban) gene is a key regulator of the pump that controls calcium cycling. Scientific names for this PLN gene mutation are c.40_42del AGA and .Arg14del.
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Latest news & blog articles
PLN Day in Murcia en Mula
More international cooperation: Pieter visits Mula, Spain, where PLN carriers live – a PLN carrier was born here back in…
An award for Dr. Kranias
Dr. Litsa Kranias is rewarded with a prestigious reward: the Basic Research Prize: ” The American Heart Association awarded its Basic…
Latest PLN Research results, developments & events
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PLN Day in Murcia en Mula
More international cooperation: Pieter visits Mula, Spain, where PLN carriers live – a PLN carrier was born here back in…
-
An award for Dr. Kranias
Dr. Litsa Kranias is rewarded with a prestigious reward: the Basic Research Prize: ” The American Heart Association awarded its Basic…
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Gala for the PLN Foundation
On April 2, 2020, DLM | Dé Lease Maatschappij B.V., is organizing a gala for the PLN Foundation. The gala…
Why our foundation?
- Conduct scientific research projects
- Stimulate partnership with PLN Institutes
- Intensify hospitals & medical centers network
- Inform about latest PLN research developments
- Support PLN patients and family members
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